音乐疗法联合正念认知疗法对造血干细胞移植患者睡眠的影响

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The Impact of Music Therapy Combined with Mindfulness-based Cognitive Therapy onSleep in Patients Undergoing Hematopoietic Stem Cell Transplantation
HUANGYanzhen,XUChunmei
(Department of Hematology,The First Affiliated Hospital of Xiamen University,Xiamen 36lO03,China)
AbstractObjective:Toexploretheeficacyof individualized music therapycombined with mindfulnessbasedcognitive thrapy (MBCT)onpatientsundergoinghematopoieticstemcelltransplantation.Methods:Atotalof8OpatientswhoreceivedhmatopoieticstemcelltransplantationintheFirstAfliatedHospitalof XiamenUniversityfromJanuary2O23toDecember224wereselectedandrandomlydividedintoacontrolgroupandanobservationgroupbytherandomnumbertablemethod,with4Ocases in each group.Thecontrol groupreceived routine nursing,whiletheobservation group was given individualized musictherapy combined with MBCTnursingonthebasisof thecontrolgroup.Beforeandafter4weeksof intervention,Polysomnography(PSG)parameters(totalsleptime,spatency,sleepeiciencywakeningfrequency)fatiguestatusPiperatigueScale-RevisedP R)],sleepqualityPitsburgh SleepQualityIndex(PSQI)]andemotional stateProfleof Mood States(POMS)]wereevaluated inthe two groupsofpatients.Results:After4 weeksof intervention,thePSGslepparameters inthetwo groups were bettrhan those before intervention,and the scores of PFS-R,PSQI and POMS were reduced compared with thoseat baseline( P<0.05 ). Furthercomparison between groups showed thatthePSG sleepparameters intheobservation groupwere beter,andthescoresof PFS-R,PSQI and POMS were lower compared to the control group ( P<0.05 ). Conclusion: Individualized music therapy combined with MBCTcanimproveemotionalstates,enhanceslpquality,educenightawakeningsandrelievefatigueinpatientswith hematopoietic stem cell transplantation.
KeywordsHematopoieticstemcel tansplantation;Musictherapy;Mindfulness-basedcognitivetherapy;Fatigue;Sleepquali ty;Emotional state;Pitsburgh Sleep Quality Index; Piper Fatigue Scale-Revised;Profile of Mood States 中图分类号:R473.5;R454.3;R395.4;R338.63 文献标识码:A doi:10.3969/j. issn. 2095 - 7130.2025.10.062
造血干细胞移植是血液系统疾病的重要治疗手段,但患者常因治疗不良反应、免疫抑制及心理压力出现严重疲乏和睡眠障碍[1]。(剩余4068字)