OSAHS 患者常规心电图Tp-e/QT、QTd与室性早搏风险的关联性研究

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Association of Conventional Electrocardiographic Tp-e/QT Ratio and QTd with the Risk of Premature Ventricular Contractions in Patients with Obstructive Sleep Apnea-hypopnea Syndrome

CHEN Ye，LUO Song （Fujian Provincial Geriatric Hospital，Fuzhou 35Ooo9，China）

AbstractObjective：ToinvestigatethecorelationbetweentheTp-e/QTratio，QTintervaldispersion（QTd）onconventional electrocardiogram（ECG），andtheriskof prematureventricularcontractions（PVCs）inpatientswithobstructivesleepapea-hypopnea syndrome（OSAHS）.Methods：Atotalof196 patientswith OSAHS who were treatedatFujan Geriatric Hospital from March 2023 to March2025 wereenroledas study participants.Acording tothe presence orabsence of nocturnal PVCs，theywere divided into the nocturnal PVC group（ n=38 ） and the non-PVC group（ n=158 ）. All patients underwent 12-lead ECG examination. Ventricularrepolarizationparameters（Tp-einterval，，QTinterval，Tp-e/QTratio，ndQTd）andslpqualityscoreswere comparedbetweenthetwo groups.Thepredictivevalueof theseECGparameters fornocturnalPVCsand theircorelation with sleepquality scores were analyzed.Results：ECG monitoring showed thatthe nocturnal PVC group had significantly higher Tp-e interval，Tp-e/QTratio，and QTdcompared with thenon-PVC group，and the diferences were statisticallysignificant（ P<0.05 ）. ThecombineduseofTp-einterval，Tp-e/QTratioand QTdhadthe highest predictiveeffciencyfor PVCoccurrence inOSAHS patients，withthe largest Youden indexofO.655，anareaunderthereceiveroperatingcharacteristiccurve（AUC）of0.859，sensitivity of 92. 11% ，and specificity of 73. 42% . Pearson correlation analysis showed that Tp-e interval，Tp-e/QT ratio，and QTd were positively correlated with sleep quality scores in OSAHS patients（ P<0.05 ）. Conclusion：Tp-e interval，Tp-e/QT ratio，and QTd areabnormallelevated inOSAHS patients withPVCs.These parameters serveas importantECG indicatorsfor predicting therisk of nocturnal PVCs and are correlated with sleep quality.

KeywordsObstructive sleep apnea-hypopnea syndrome;；Nocturnal premature ventricularcontractions;；Electrocardiogram；Predictive value；Clinical significance

中图分类号：R364.4;R338.63 文献标识码：A doi：10.3969/j.issn.2095-7130.2025.10.001

阻塞性睡眠呼吸暂停低通气综合征（ObstructiveSleep Apnea-Hypopnea Syndrome，OSAHS）主要由上气道解剖结构狭窄、肥胖、神经肌肉功能异常等因素引发，致使睡眠时上气道软组织松弛塌陷，阻碍气流通过[1-2]。（剩余6327字）