非营养性甜味剂对代谢的潜在影响

中图分类号：TS202.3 文献标志码：A 文章编号：1674-0270（2025）36-0152-03

Abstract： The global burden of metabolic diseases continues to increase.As ideal substitutes for sucrose，nonnutritive sweteners （NNS）are being used increasingly widelyinthe food industry.Thisarticlesystematicalyreviews the mechanisms underlying the metabolic efects ofboth natural and synthetic NNS from a food science perspective.It discusses theirapplication value in sugar-reduction strategiesforfoods andtheir potential risks.Byanalyzing the effects of diffrent types of sweetenerson blood glucose level regulation，their impacton gut microbiota，and theirassociation with weightcontrol，itdemonstrates thattheir "non-nutritive"characteristicdoesnotequate tometabolicinertess.The study points out that the metabolic efects ofNNS inthe humanbody exhibit significantdose dependencyand individual variability，necessitating theestablishmentofamore scientificevaluationsystemfortheirapplicationinfoods，tosupport the rational use of NNS，the optimization of product formulations，and future research.

Key Words： non-nutritive sweeeners; efect on metabolism; food aditives; gut microbiota; sugar reduction strategy

代谢性疾病已成为全球公共卫生领域的重大挑战。（剩余3786字）