脸板腺功能障碍与睡眠质量之间的相关性研究

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Correlation Study Between Meibomian Gland Dysfunction and Sleep Quality

ZHU Mingyue，CHEN Xinqin，CHEN Wanling （Department of Ophthalmology，First Hospital of Longyan，Longyan 3640oO，China）

AbstractObjective：To analye the correlation between meibomian gland dysfunction（MGD）and sleepquality.Methods： A single-centerretrospectivestudywasconducted，colectingpatientswithMGDwhovisitedtheophthalmologyoutpatientclinicof theFirstHospitalofLongyanfromJune2O24 toJune2O25andmetinclusioncriteria.Generalclinicaldata werecolected.Based on the Pittsburgh Sleep Quality Index（PSQI），patients with PSQI⩾14 were classified as the sleep disturbance group，and those with PSQI <14 were clasified as the control group. Diferences between the two groups were analyzed to clarify the correlation betwen MGDand sleepquality.Results：A total of3OO MGDpatients were included，with105 in the sleepdisturbance groupand 195 in the control group.There were no significant diferences in gender，age，or disease duration between the groups（ P>0.05 ） Thesleepdisturbancegrouphadhighersoresiocularsufacediseaseindex，ornealfluoresceinsaining，yelidmarginoology，meibomianglandscretioncapacity，ndmeibomiansecretionquality，hiletearfilmbreakupimewasshorterandbsaltear secretion scores were lower compared with the control group（ P<0.05 ）. Conclusion： As sleep quality declines in MGD patients， ocularsurfaceparameterssuchastearfilmbreakuptimeandcorealfluoresceinstainngtendtoworse，eflectingdeterioratioof ocularsurfacehealth.Thiscorelationsuggests thatimprovingsleepqualityinMGDpatients mayhelpoptimizeocularsuface parametersand promoterecoveryofocularsurface health.Sleepdisturbances may exacerbate MGD，adverselyafecting ocularsurface health.

KeywordsMeibomiangland dysfunction;Sleepquality；Sleepdisturbance score；Eyelid margin morphology；Meibomiangland secretion capacity；Meibomian secretion quality；Tear film breakup time； Correlation 中图分类号：R777.1;R338.63 文献标识码：A doi：10.3969/j. issn. 2095 -7130.2025.12.012

睡眠作为一项极为关键的生理过程，承担着人体功能整合、体能恢复以及记忆巩固等重要职责，是维持正常生活状态必不可少的环节[1]。（剩余5861字）