5-羟甲基糠醛生物法制2.5-呋喃二甲酸技术以及应用进展

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中图分类号：TQ251.1；Q81 文献标志码：A 文章编号：1671-0460（2026）01-0151-10

Abstract： 2，5-Furandicarboxylic acid （FDCA），as a green alternative to petroleum-based aromatic monomers，has broad applicationprospects inthe fieldofbio-based materials.Itscatalyticconversion from5-hydroxymethylfurfural（HMF） is acurrentresearch hotspot.Inthis paper，te technicalandapplication progress ofbiologicalproductionofFDCA from HMF was reviewed.Firstly，the technological basis for preparing HMFfrom biomass raw materials through hydrolysis and dehydration was outlined; then， the technical routes forcatalytic oxidation of HMF to FDCA were summarized， focusing onthe advantages of biological methods，and the principles，characteristics and research status of biological conversionroutes wereelaborated;finally，theindustrializationprocessofthis technologywasanalyzed，thecurent botlenecks such as efciency and cost as well as future breakthrough directions were pointed out，providing some reference for the technical optimizationand industrial applicationofbiologicalconversionofHMF toFDCA.

Key words： 5-Hydroxymethylfurfural; 2，5-Furandicarboxylicacid; Microorganism; Wholecell; Enzyme; Biocatalysis

随着现代社会对化石能源的高度依赖和深度消耗，化石能源造成的全球气候变化和环境污染问题日益严重，寻求能够替代化石资源的可再生能源已成为一个重要的研究课题。（剩余27246字）