乳类激素残留检测的样本前处理技术改进与验证

关键词：乳类激素残留；样本前处理；基质干扰；固相萃取；方法验证中图分类号：TS252.7 文献标志码：A 文章编号：1674-0270（2026）01-0053-04DOI： 10.16043/j.cnki.cfs.2026.01.014

Improvement and Verification of Sample Pretreatment Technology for the Detection of Hormone Residues in Milk

ZUO Guoqiang'， GAO Yang'，LU Lihua² （1.Inner MongoliaAutonomousRegionScientificResearch InstituteofFoodQualityandSaftyInspection，HohhotOO，China; 2.Inner Mongolia Autonomous Region Institute of Product Quality Inspection， Hohhot O1oO7o， China）

Abstract： The detection of hormone residues in milk is a critical technical component for ensuring the quality and safetyof dairy products，and the effectivenessof sample pretreatment directlyafects the accuracyandreliabilityof analytical results.Owing to the complex matrix ofmilk samples，high contents offatand protein，as wellas the wide varietyandlowconcentration levelsofhormones，conventional pretreatment methodsstillexhibitcertain limitations in terms of recovery，purificationeficiency，andoperational stability.Inresponse totheanalyticalrequirements formilk hormone residue detection，the applicabilityof diferent pretreatment techniques in dairy matrices is systematically evaluated.Emphasis is placed on improving sample pretreatment through process optimization，enhancement of purification performance，and control of matrix interference，andthe efectiveness ofthe improved methods is verified using methodological performance indicators.

Key Words： milk hormone residues; sample pretreatment; matrix interference; solid-phase extraction; method validation

随着乳制品消费量持续增长，乳类产品中激素残留问题成为食品安全监管关注的重点。（剩余5414字）