食品基质中D族维生素物质检测方法的研究进展

关键词：维生素D；样品制备；固相萃取；色谱分析

中图分类号：TS207.3 文献标志码：A 文章编号：1674-0270（2026）01-0037-04

DOl:10.16043/j.cnki.cfs.2026.01.010

Research Progress on Detection Methods ofVitamin D Compounds in Food Matrices

HUANG Mengkai, LIU Yu (Anhui Institute for Food and Drug Control,Hefei 23Oo51, China)

Abstract: Vitamin Dand its analogs,as fat-soluble vitamins,playa critical role inthebiological functions of humans andanimals.Studies have confirmed that their deficiency is closely associated with the development of skeletal and extra-skeletal diseases (such as cardiovascular diseasesand immune dysregulation).Vitamin D is primarilyderived from the biotransformationof7-dehydrocholesterol in theskinunderUV-Bradiation,anddietaryintake (including natural foods and nutritional supplements)isalso crucialfor regulating its levelsinthebody.Therefore,establishing eliable analyticalmethods todetectthecontentof vitaminDanditsanalogs infoodsandsupplements isofsignificantimportance for preventing deficiencyand related diseases.This article reviews the research progressin the detection methods of vitaminDanditsmetabolites infood matrices,withafocus onchromatographic techniques combinedwithtraditionaland novel sample pretreatment methods.Theapplicability,sensitivity,imitsofdetection,andoperationalsimplicityof se methods are analyzed to provide reference for related research.

Key Words: vitamin D; sample preparation; solid-phase extraction; chromatographic analysis

维生素 ΔD3 （胆钙化醇）和维生素 D2 （麦角钙化醇）是脂溶性甾体维生素，在钙磷代谢与骨骼健康中发挥核心作用，具有广泛的多效性功能。（剩余8022字）