血清TBIL、HbA1c、hs-CRP、血脂指标联合检验在2型糖尿病患者中的检验价值

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[中图分类号]R587.1 [文献标识码]A [文章编号]1672-4062（2026）03（a）-0056-04

TheValue of Combined Testof Serum TBIL，HbA1c，hs-CRP and Blood LipidIndexes inPatientswith Type2DiabetesMellitus

SULiming，LIXincai，LIShuting，WANGYan Department of Laboratory，Longyan First Hospital，Longyan 364Ooo，Fujian，China [Abstract] Objective To analyze the expression and significance of total bilirubin（TBIL），glycated hemoglobinAlc （HbA1c），high sensitive C-reactive protein （hs-CRP）andblood lipid combined test in type2 diabetesmellitus. Methods FromJanuary to May 2025，42 patients with diabetes diagnosed and treated in the Departmentof Laboratory ofLongyan First Hospital were selected as theobservationgroup，and42 healthysubjects were selected asthecontrol group.The levels ofserum TBIL，HbA1c，hs-CRPand blood lipids were detected and comparedbetween theobservationgroup and thecontrol group，and the diagnostic eficacy of the combined test was analyzed.The sensitivity and specificity werecalculated，andthedata diffrences betweentheclinical indexesof the twogroups were evaluated. Results The levelsofserum TBIL，HbAlc，hs-CRPand blood lipid in thecontrol group werebeterthan those in the observation group，and the differences were statistically significant （all P<0.05 ）.The areas under curve of combined detection was greater than thatof single detectionof peripheral blood HbA1c，and the sensitivity and specificity of combined detection were higherthanthoseof peripheralblood HbAlcdetection.Conclusion Thecombined detection of serum TBIL，HbAlc，hs-CRPand blood lipid levels in patients with type2diabetes melitus hasa gooddiagnostic efctandsignificance，and thedegreeofdiabetic lesionsiscloselyrelated tothelevelofserumindicators，whichcan provide scientific basis for clinical diagnosis and treatment.

[Keywords]Serum total bilirubin; Glycated hemoglobinAlc;Blood lipid;Type2diabetesmelitus;Combined test

2型糖尿病（type2diabetesmellitus，T2DM）属于一种较为常见的临床慢性基础性疾病，发病率较高，若不及时控制血糖水平，则会使心血管疾病患病风险升高，并且本病症的发生、发展还会极大影响患者的日常生活状态，其相关并发症也是造成生活质量下降以及患者死亡的主要原因[2。（剩余4426字）