HbA1c、FPG检测在2型糖尿病和糖尿病前期筛查中的运用及筛查界值分析

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[中图分类号]R587.1 [文献标识码]A [文章编号]1672-4062（2026）01（b）-0077-04

AnalysisoftheApplicationandThresholdValueofHbA1candFPGTestingin Screening Type2DiabetesMellitusand Pre-diabetesMellitus

YANG Yi，DING Huihong

Department ofLaboratory，Shougang Shui Steel Hospital，Liupanshui 553oOo，Guizhou，China [Abstract] Objective To explore the application and threshold value of glycated hemoglobin A1c （HbAlc）and fasting plasma glucose （FPG） in the screeningof type2diabetes melltus （T2DM）and pre-diabetes melltus （PDM）.Methods A total of10OpatientswithT2DMorPDMwho were treated inShougang Shui StelHospitalfromAugust2024toAugust 2025 were conveniently selected.Among them，5O patients with T2DM were T2DM group，50 patients with PDM were PDM group，and 50 healthy subjects were selected as control group.The HbA1c andFPG of each group were detectedandcompared，andthecritical valueandpredictiveeficacyofscreening T2DMandPDMwereanalyzedbyreceiver operating characteristic curve.Results FPG and HbAlc in the PDM group and the T2DM group were higher than those in thecontrol group，and the T2DM group was higher than the PDM group，the diffrences between the three groups were statistically significant （all P <0.05）.The sensitivity and specificity of FPG combined with HbA1c detectionforT2DMand T2DMandPDM were higher thanthoseofFPGand HbAlc singledetection.Conclusion The combined detection of HbAlcandFPG has high accuracy in the screening of T2DMandPDM，and can improve the screening efficiency compared with single detection.

[Keywords]Type2diabetes melitus;Pre-diabetesmellitus;Screening;Glycated hemoglobinAlc;Fasting plasma glucose; Threshold value

糖尿病（diabetesmellitus，DM）是一种以慢性高血糖为典型特征的代谢性疾病，可引起神经、血管、肾脏等多器官、系统并发症，其作为一种慢性非传染性疾病已成为危及全球人类健康的重大问题[1]。（剩余4667字）