对比微量泵持续泵人与静脉滴注小剂量胰岛素在糖尿病酮症酸中毒中的疗效

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[中图分类号]R587 [文献标识码]A [文章编号]1672-4062（2026）01（a）-0009-04

Efficacy Comparison of Continuous Micropump Infusion and Intravenous Infusion ofLow-dose Insulinin DiabeticKetoacidosis

ZOULifang，XIAO Shuhua，LUO Zhongyan Department of General Practice，Longyan People's Hospital，Longyan 364Ooo，Fujian， China [Abstract] Objective To compare the efficacy of continuous micropump infusion and intravenous infusion of lowdose insulininthetreatmentof diabetic ketoacidosis （DKA）.MethodsAtotalof6OpatientswithDKAwho were treated in Longyan People's Hospital from November 2023 to July2025 were convenientlyselected asthe study subjects.They were divided into groups according to different treatment methods，with 3O cases in each group.The controlgroupreceived continuous intravenous infusionoflow-dose insulin，whilethestudy groupreceivedcontinuous micropump infusionof low-dose insulin.Theblood glucose level，bloodgas level，serum index improvement timeand complication rate were compared between the two groups.Results After treatment，thelevels offasting plasma glucose and glycated hemoglobinA1cinthe study groupwere lower than those inthecontrol group，and thedifferences were statistically significant （all P<0.05 ）.Theblood gaslevels （arterial blood pH value，bicarbonate level and carbon dioxide combining power）inthe study group were beterthan those inthecontrol group，and the diferences were statistically significant （all P<0.05 ）. The time of blood ketone turning negative and pH value recovery in the study group were shorter than those in the control group，and the differences were statistically significant （all P<0.05 ）. The incidence of complications in the study group was 6.67% （2/30）， which was lower than 26.67 % （8/30） in the control group， and the difference was statistically significant （ χ2 =4.320， P <0.05）.Conclusion Continuous micropump infusion of low-doseinsulininthetreatmentofDKAcanmore effctivelycontrolblood glucose，improve bloodgasstatus，shorten therecovery time of serum indexes，and reduce the incidence of complications.

[Keywords]Diabetic ketoacidosis; Continuous micropump infusion; Intravenous infusion; Low-dose insulin

糖尿病酮症酸中毒（diabeticketoacidosis，DKA）是糖尿病（diabetesmellitus，DM）常见的严重急性并发症之一，以高血糖、高血酮、代谢性酸中毒为主要特征。（剩余5316字）