单分散微米级 PMMA/PGMA 微球的制备

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引用格式：，等. 单分散微米级 PMMA/PGMA 微球的制备[J]. 当代化工，2026, 55（4）：821-824.

LI Kexin, ZHANG Shuai, YU Xiaohui, et al. Preparation of Monodisperse Micron-Sized PMMA/PGMA Microspheres [J]. Contemporary Chemical Industry, 2026, 55(4): 821-824.

1 ， 1 ， 1 ，毛小雨 1 ，李明昊 1 ，李佳锡 1 ，石山 1 ，郭保胜 2

（1. ， ；

2. ， ）

中图分类号：TQ327.5

文献标志码：A

文章编号：1671-0460（2026）04-0821-04

Preparation of Monodisperse Micron-Sized PMMA/PGMA Microspheres

LI Kexin 1 , ZHANG Shuai 1 , YU Xiaohui 1 , MAO Xiaoyu 1 , LI Minghao 1 , LI Jiaxi 1 , SHI Shan 1 , Guo Baosheng 2

(1. School of Materials Science and Engineering, Shenyang University of Chemical Technology, Shenyang Liaoning , China;

2. Beijing Nano Separation Technology Development Co., Ltd., Beijing , China)

Abstract: Monodisperse poly(methyl methacrylate) (PMMA) microspheres (3.8 μm in diameter) were synthesized via dispersion polymerization. These seed particles were then used to prepare uniform crosslinked PMMA/poly(glycidyl methacrylate) (PGMA) microspheres through a one-step swelling method. The results showed that PMMA/PGMA microspheres exhibited a narrow size distribution, with the dominant peak in laser particle size analysis at around 5.5 μm.

Keywords: Seed swelling polymerization method; Monodisperse; Micron-sized microspheres; Polymethacrylate; Chromatography; Polymers

有机高分子微球因可调控的尺寸、组成和结构形态，在生物工程医药 [1-3] 和电子信息工业 [4-6] 领域备受青睐。（剩余8052字）