血清C肽与糖化血红蛋白联合检测对糖尿病诊断 灵敏度和特异度的影响

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中图分类号：R446文章编号：1006-1959（2026）05-0156-04

文献标识码：A

DOI：10.3969/j.issn.1006-1959.2026.05.029

Effect of Combined Detection of Serum C Peptide and Glycosylated Hemoglobin on the Sensitivity andSpecificityofDiagnosis in DiabetesMellitus

PANKai，QIUYi，YANXiying

（DepartmentofClinicalLaboratory，Rushan HospitalofTraditionalChinese Medicine，Rushan264599，Shandong，China）

Abstract：ObectiveTdyhtofombideteoofeCpeptidndglycosylatdmogloboesitityndsif diagnosisidabetesmelltusMetodsFromMarch22toFebruary24，9dabetesmelituspatientsnd9ealhysubjecsishan HospitalofTraditionalChineseMedicinewereseletedastheresearchobetsandtheyweresetasthestudygoupandthecotrolgroup respectivelyTelevelsofruCpeptideandyosylatedmoglobnereeteedTevelsofruC-peptidandlyosylaedglobn werecomparedtwntoupsdetiotedaosticfacofingestdoidsteopedls levelofserumCpeptideinthestudygroupaslowerthanthatinthecontrolgrouphilethelevelofHAlcashigerthanthatintheotrol group（ P< O.05）.TherewasnosignificantdiferenceinthedetectionrateofdiabetesbetwensingleHbAlcandsingleserumCpeptide（ P> 0.05）. The detection rate of combined diagnosisof diabetesmelituswas higher than that of single test（ P <0.05）.There was no significant difference in the diagnostic efficacy between single HbAlc and single serum C-peptide test （ P> 0.05）.Compared with the single test，the sensitivity and accuracy of the combined test were higher P<0.05） .Conclusion Serum C-peptidecombined with glycated hemoglobindetection hasahighapplication value in the clinicaldiagoslioseldef basis forthetreatmentofclinicians，helpspatientsecover，improvessymptoms，anddelaystheoccurreneofomplications.

Keywords：Serum C-peptide;Glycosylated hemoglobin;Diabetesmellitus

糖尿病是一种由糖代谢异常引起的慢性内分泌疾病，随着糖尿病的发病率逐年上升，其诊断和治疗也日益引起人们的关注。（剩余5329字）