从脾分期论治克罗恩病的临证思路
【中图分类号】R256.3 【文献标志码】A 【文章编号】1007-8517(2026)06-0018-05
DOI:10. 3969/j. issn.1007-8517.2026. 06. zgmzmjyyzz202606005
Clinical Thinking on the Staged Treatment of Crohn's Disease from the Perspective of the Spleen
XU Erping? HenanUniversityofChineseMedicine,Zhenzhou45OO46,China
Abstract:Crohn'sdiseaseisachronicinflammatory boweldiseaseof unknowncause,withanincreasingincidenceinrecent years.Itcommonlyaffectsyoungadults,andcurrent treatents inmodernWestermedicieoftenyieldunsatisfactoryesultsadcay sideeffects.Thisarticlesugeststhatalthough Crohn'sdiseasemanifestsintheintesties,tecorepathologicalorganisthspleen. SpleendeficiencyisidentifedasthekeypathomechanismofCrohn'sdisease.Intheearlystage,spleendeficiencyleadstoimpired transportationandtransformationresultingininstabilityofdefensieqi;inthemdlestage,spleendficiencycombineswithdamp heat,causingdisarmonybetweentheutritiveanddefensiveqi;ntelatestage,spleendeficiencyrsultsinqistagnationandtheinterlockingofphlegmandblodstasis.Treatmentstrategiesvarybystage:Earlystage:Strengthenthespleenandstomach,bostqi, andstabilizetheexterior.Recommendedformula:ShenlingBaishuPowdercombinedwithYupingfengPowder,modifedasneeded. Middle stage:Clearheat,drydampness,andharmonizethenutritiveanddefensiveqi.Recommended formula Baitouweng Decoction combinedwith Huangi Guizhi WuouDecoctioninmodicationsLatestage:Tonifyqiandthespleen,promotebloodcirculation,and resolveplegmRecomendedfoula;DhuangMudanDecoctionadjustedacordinglyAclinicalcaseisalsopresentedtosprt thefeasibitndeficacyoftreatingCron'sdiseasebydiferenatingbasedonsplenpates.Flexiblerbalprescriptionsacoding todiseaseprogesioncanelpestoreteslenandstomach'stansfoativefunctions,feinganewapproachandstrateforcliical treatment.
Key Words:Crohn's Disease;Spleen; Inflammatory Bowel Disease;Spleen Deficiency;Stage-based Treatment
克罗恩病(crohnsdisease,CD)是一种病因不明发生在胃肠道的非特异性自身免疫系统疾病,属消化道慢性炎症疾病范畴,主要以腹痛、腹泻、体重下降、疲劳、发热,生长缓慢等为主要症状,甚者可能出现腹部包块、瘘管形成、肛门直肠周围病变等,起病隐匿,病程迁久不愈,且易复发,CD病理机制尚不明确,目前认为多因先天遗传,免疫因素,环境因素,肠道菌群因素,心理因素等相互作用有关[。(剩余8149字)