基于MR静脉期影像组学特征预测胃癌微卫星高度不稳定状态

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中图分类号：R735.2 文献标识码：A文章编号：1006-1959（2026）03-0042-06

DOI：10.3969/j.issn.1006-1959.2026.03.007

Prediction ofMicrosatellite Instability-high of Gastric CancerBased on MRVenousPhaseRadiomicsFeatures

PENGRongl，ZHANG Zeming1，WANG Zhiqing1，LIBin1，QINGLiping1，WANGJinxing² （DepartmentofRadiology，Medical ImagingCenterl，PainDepartment²，Panzhihua CentralHospital， Panzhihua ，Sichuan，China）

Abstract：ObjectiveTinvestigatetheabilityofradiomicsbasedonmagneticresoancevenouspaseimagingtoredicttheelite istabitysido MSI-Hpositivecasesand38S-HnegativecasesItwasandomlydvidedintoatrainigset（n=7）ndateset（n=52）inati RadiomicfeaturesereetractedromortalvenouspaseimagesbDicesoftare.Univarateanalysisadleastabsoluteshagead selectionoperatorSetsetelecteaturesndendiosaturesstructedsinglsticegreioali ReceiverpeatigracteiticOCuealslatiralyisndsiaisC）edtee performance.ResultsTheareaunderthecurve（AUC）forevaluatingtheMSI-Hstatusofgasticcancerinthetrainingsetwas0.886（ 95%Cl; （204 0.789-0.983）siiU）ts andspecificiyas92.TecalibatiocureshoeddfitingeThecisiocueowdattetraingsendteestsdod returns.Conusiosedosedesatusfstriccfielyedcid important reference value for clinical understanding of MSI-H status.

KeyWords：Gastric cancer;Microsatelite instability;Magnetic resonance imaging;Radiomics

胃癌（gastriccancer）是最常见的恶性肿瘤之一，其死亡率排名全球癌症第四[]。（剩余8558字）