虫草菌51和55菌株发酵对小茴香代谢产物的影响

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关键词：真菌发酵；虫草菌（Cordycepsspp.）；发酵；小茴香；代谢产物

中图分类号：TS201.3；R284.2 文献标识码：A

文章编号：0439-8114（2026）01-0116-08

DOI：10.14088/j.cnki.issn0439-8114.2026.01.020 开放科学（资源服务）标识码（OSID）：

Effects of fermentation with Cordyceps spp.strains 51 and 55 on the metabolites of fennel

XUYu-shengab，CHENQi-qi，CHENLonga，LI Xiao-jinga，YANGLi-yea，ZHAOFenga，b （a.Collgeofndofe;bnIteaalJntLbatorfigitaloseandpsmovtiofiLat Resources;c.Personnel Office，Pu'er University，Pu'er 665ooo，Yunnan，China）

Abstract：Metabolomicswasusedtoanalyzethechangesinmetabolites（X51，X55）andkeymetabolicpathwaysinfennelbeforeand afterfermentationwithCordyepsspp.strains51and55.Theresultsshowedthatfermentationalteredthemetabolicprofileoffennel comparedtothecontrol group（XK）.ThepaersofdiffrentialmetabolitechangesweresimilarbetweenXKvsX51andXKvsX55 comparisons，with310and297upregulatedmetabolites，respectively，primarilyaminoacidsandtheirderivatives，and423and400 downregulated metabolites，respectively，primarilyphenolicacids.InboththeXKvsX51andXKvsX55comparisons，themainupregulatedmetabolitesincludedL-ornithineandcyclo（L-leucine-trans-4-hydroxy-L-proline），amongothers.Theupregulationof thesemetabolitesmightbecloselyelatedtothepharmacologicallyactivecomponentsoffenel.ThediferentialmetabolitesfromXK vsX51andXKsX55omparisoswereanlyeichdinosyesisofscondarymetablitesiosythesisofcofactosd synthesis of aminoacids.Theannotation proportionof the biosynthesis of secondary metabolites pathways allexceeded 39% ，indicating that this pathway might play a core regulatory role during the fermentation process.

Keywords：fungal fermentation;Cordycepsspp.;fermentation; fennel;metabolites

药材小茴香（FoeniculiFructus）为伞形科植物香（FoeniculumvuLgareMill.）的干燥成熟果实[i]。（剩余6969字）