恩施州不同海拔五倍子没食子酸含量与生物活性评价

打开文本图片集

关键词：五倍子（Gallachinensis）；恩施州；海拔；没食子酸；抑菌活性；抗氧化活性；抗癌活性中图分类号：R284.2；R285.5 文献标识码：A

文章编号：0439-8114（2026）01-0111-05

DOI：10.14088/j.cnki.issn0439-8114.2026.01.019 开放科学（资源服务）标识码（OSID）：

Evaluationof gallicacidcontentandbioactivityinGallachinensisatdifferentaltitudesin Enshi Prefecture

GAOXiang1，²，ZHENGRun-bo1，²，ZHUYue1²，LI Yu2 ，WANGQing-fang²，LUOKai1，HEMei-jun 1，2 ，SHI Ai-hual （1.Colegofisiebsubdel Sciences/NatioaliebaldicustrolEompseEptalaishioube）

Abstract：GallachinensissamplescollctedfromEnshi Prefectureataltitudesof1020m（L-GC）and168Om（H-GC）wereutilized.TegallccidotetaeteridbyHCndteibactealicanerndtiodantactiviisfttct were systematically compared. The results showed that the gallic acid content of H-GC （ 492.8mg/g ）was significantly higher than that ofL-GC（ 203.9mg/g ）. In terms of antioxidant activity，the H-GC extract（H-MEGC） exhibited a DPPH scavenging IC50 value of 5.64μg/mL ，which was significantly better than that of the L-GC extract（L-MEGC， IC50 =19.96 μg/mL ）.Both extracts significantly inhibited the proliferation of A549 lung cancer cells，with IC50 values of 25.72μg/mL （L-MEGC）and 27.43μg/mL （H-MEGC），and therewasnosignficantdierencebetweenthetworous.Inantbacterialasss，H-MEGCat10Og/Lshowedstrongribiion againstsometestedstrains（Bacillssubtis，Bacilusthuringiensis，ndAcinetobacterbumanii）comparedtoL-MEGC.Withincreasingalitde，thegallcacidcontent，antioxidantcapaciy，andantibacterialactivityofEnshiPrefectureGllchnensiginst certain strains were enhanced，while its inhibitory effect on A549 cels was not significantly affected.

KeyWords：Gallinensis；EshPrefecture；altitude；galiccidantibacterialactivity；antioxidantactivitynticancctiiy

五倍子（Gallachinensis）又名盐麸叶上球子、文蛤、百虫仓，药用记载首见于唐代《本草拾遗》，是中国使用历史悠久的中药材。（剩余9316字）