影像学检查在慢加急性肝衰竭中的应用

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Abstract：Acute-on-chronicliverfailure（ACLF）isasyndromeofmultipleorgan failureonthebasisofunderlyingchronic liver diseaseandhasanextremelyhighshort-termmortalityrate，whilethereisstillalckofunifiddiagnosticcriteriaaroundtheorld. RadiologyplaysanimportantroleintheevaluatioandprognosticpredictionofACLF，constitutingamulti-dimensionalsesmnt systemcovering morphology，function，and hemodynamics.Computed tomographycanbeusedforthemeasurementoflivervolume andthediagnosisof sarcopeniabyprovidingkeymorphologicalandnutritionalparameters.Magneticresonanceimaging（MRI）， especiallygadobenatedimeglumine-enhancedMRI，nablesquantitativeassessmentofliverfunctionandhascriticalsignificance forpredictingshort-termsurvivalrate.UltrasonographyandelastographytechniquesfacilitatetheearlywaringofACLFosetand thedynamicmonitoringof itsprogresiothrough noninvasivemeasurementof liverstifessand hemodynamicparameters.This articlesystematicallyreviewsthepivotalroleof thesethreeimagingmodlitiesinthediagnosisandmonitoringofACLF，and integrating thestrengthsofmultipleimaging techniques withclinicalindicators toconstructdiagnosticandprognosticmodelsmay become a key future direction for achieving early intervention and improving clinical outcomes in ACLF.

Research funding： Jilin Provincial Healthcare Talent Special Program（JLSWSRCZX2023-3） KeyWords：Acute-on-Chronic Liver Failure;Tomography，X-Ray Computed; Magnetic Resonance Imaging； Utrasonography

肝硬化是一种在全球范围内广泛存在的疾病，其病因多种多样，涉及病毒感染、代谢性疾病、中毒性损伤以及自身免疫缺陷等诸多因素。（剩余15435字）