无创呼吸机标准化治疗联合氨茶碱在慢阻肺并I型呼衰中的应用

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Abstract： Objective：To explore the clinical efect of non-invasive ventilator standardized treatment combined with aminophylline in patients with chronic obstructive pulmonary disease （COPD） complicated with type I respiratory failure.Methods： Eighty patients with COPD complicated with type I respiratory failure admited to the Baiyin Central HospitalofGansu Province fromJune2023 to June2024 were selectedas theresearch objectsandrandomly divided into a control group and an observation group， with 40 cases in each group.The control group received basic treatment + aminophylline，while the observation group received basic treatment + aminophylline + non-invasive ventilator standardized treatment.The lung function and blood gas indicators—partial pressure of oxygen （PaO2） and partial pressure of carbon dioxide （PaCO2） ）—of the two groups of patients were compared. Results： The lung function and PaO2 of patients in the observation group were higher than those in the control group （P<0.05） ;The PaCO2 of patients in the observation group was lower than that in the control group （P<0.05） . Conclusion：The application of noninvasive ventilator standardized treatment combined with aminophyline in COPDcomplicated with type II respiratory failure can improve pulmonary ventilation function and thereby correct abnormal blood gas indicators.

Keywords： non-invasive ventilator standardized treatment; aminophyline;chronic obstructive pulmonary disease; type I respiratory failure

0引言

慢性阻塞性肺病（ChronicObstructivePulmonaryDisease，COPD），也称为慢阻肺，是临床常见的呼吸道疾病，文献指出[]，世界范围内该病的发生率约在 9% 左右。（剩余4004字）