莫西沙星治疗对轻中度慢性阻塞性肺疾病急性加重期患者呼吸困难程度、肺功能的影响

打开文本图片集

关键词：莫西沙星；慢性阻塞性肺疾病；急性加重期；肺功能中图分类号：R563 文献标识码：A文章编号：

DOI：10.3969/j.issn.1006-1959.2026.04.029

Abstract：ObjetiveTudytetofoxifloacosedpumoaryfuctioinpatintswicuteeacebatioofdtoerate chronicobstructivepumoarydisease（OPD）MetodsThisstudyincluded9patientstingtheiteriaforcuteexacerbatioofildto moderateCOPfromourospitalduringtheperiodofJanuarytSeptember24.atientsererandomizedviaaandomumbertable4patients assignedtotheoutieopheeediperacildobacmfeoilemang5ts studgrouperratedioiflacidooddododeetlicalacyeofpaoe） pulmonaryc rash）werecomparedetwenthetogoupsesultsesudygoupemostratedasignfcantlyighertotaltreatmentefectiveate94.9 % ） compared to the routine group （85.29 % ）（ Pe <0.05）.Aftertreatment，thedegreeof dyspnea （mMRCscore），pulmonaryfunctionindexes （FVC，FEVi）and inflammatoryiees（WCCinetgouereiproedoparedithoforetreatitcosintdyoing superior to those in the routine group（ P< 0.05）.The study group demonstrated asignificantly lower incidence of adverse reactions（5.71 % ）compared with the conventional group （14.71 % ）（ P <0.05）.Conclusion Moxifloxacin iseffectivein the treatment ofpatients with mild to moderate acute exacerbatifsiiisgoao reducing the incidence of adverse reactions.

Key Words：Moxifloxacin; Chronic obstructivepulmonary disease; Acute exacerbation;Pulmonary function

慢性阻塞性肺疾病（chronicobstructive pul-monarydisease，COPD）对患者造成不可逆的气流受限，尤其是发生感染、吸入有害烟雾颗粒时会诱发急性发作，导致呼吸系统症状加剧，如痰量增多、呼吸困难等[。（剩余5149字）