类风湿关节炎表观遗传修饰中的microRNAs的研究

中图分类号：R593.22文献标识码：A

DOI：10.3969/j.issn.1006-1959.2026.04.003 文章编号：1006-1959（2026）04-0012-06

Study onmicroRNAsin Epigenetic ModificationofRheumatoid Arthritis

ZHANGMing1²，ZHOUShuhong³，CHENYing3，ZHANGZhaocui³，LI Zijia² （1.TheFirstClinicalMedical CollgeofGansu UniversityofChineseMedicine，Lanzhou73oooo，Gansu，China; 2.DepartmentofImmunorheumatology，Zhangye Second People'sHospital，Zhangye7340oo，Gansu，China; 3.Department of Immunorheumatology，Gansu Provincial Hospital，Lanzhou 73oooo，Gansu，China）

Abstract：tdtiiscatooueaseEigeneicodatilatethtosef synoviumandimmuecelsAtpresent，theresearhoigeneticodificaioinlyfusesomcRAs（miAs）.RAsarealo codingRNstatplapoatoleineagessofRAbyndgteegerRRNndstroingtherastooftae genes.ThisarticlesummazestheesearchprogressofinRAinntyearsevealsooftemecanismsofRAathogsisd providesabasisoarlosissesintttspoeoyforkeded

KeyWords：microRNAs;Rheumatoid arthritis;Disease activity;Biomarkers;Epigenetics

类风湿关节炎（rheumatoidarthritis，RA）是一种慢性炎症性自身免疫病，可引起关节及关节外的损伤，病因尚不清楚。（剩余15926字）