国内外心力衰竭治疗药物经济学研究的差异比较

打开文本图片集

中图分类号R956 文献标志码A 文章编号 1001-0408（2026）05-0626-07

DOI 10.6039/j.issn.1001-0408.2026.05.13

Comparison of the differences of domestic and foreign pharmacoeconomic research on heart failure medications

SHEN Ruijial2， YANG Xiaoyul，SUN Defeng²，LI Weiya'， ZHAO Zhenying1（1. Dept.of Pharmacy，Tianjin People’sHospital/theFirst Afiliated Hospitalof Nankai University，Tianjin 300l21，China；2.Schoolof Pharmacy，TianjinMedicalUniversity，Tianjin30oo70，China）

ABSTRACTOBJECTIVETo providea basis for aligning Chinese pharmacoeconomic research on heart failure（HF）with interationalstandards.METHODSAqualitivecomparisonofdomesticandglobalHFpharmacoeconomicstudieswasconducted acrossfourdimensions：researchmethodsandmodelaplicationresearchperspectivesandendpoints，datasourcesandparameter selection，andpolicy translationand practical impact.RESULTS& CONCLUSIONsGlobal studiespredominantlyutilizelongtermdynamicmodels，societalperspectives，realorlddataintegration，nddirectlyforeimbursementdecisios.Coersely domesticresearchoftenreliesonshort-termsimplifiedmodels，asinglehealthcaresystemperspectives，literature-deriveddata，and individualmedicinerecommendations.Futuredomesticstudiesshouldtransitiontolong-termdynamicmodeling，developlocalized disease-specificutitydatabasesviabigdata，establishreimbursement-linkedclosed-loopmechanisms，andfostermuidisciplinary collaboration to optimize healthcare resource allocation.

KEYWORDSheart failure medications；pharmacoeconomicresearch；intermational experience；cost-effectivenessanalysis；costutility analysis；real-world data； localization；health insurance decision-making

心力衰竭（以下简称“心衰”作为全球重大公共卫生挑战，其疾病负担正随人口老龄化持续加重。（剩余16456字）