七叶皂苷钠的药理作用及临床药物联用

[摘要]七叶皂苷钠作为一种天然的植物药，具有抗炎、抗水肿、抗渗出、抗自由基、抗分泌、调节血脂、降血糖、保护神经和抗肿瘤等诸多药理作用。此外，七叶皂苷钠与其他药物联合使用时，在临床应用方面具有较好的疗效。本文对国内外七叶皂苷钠药理作用以及药物药效学相互作用进行综述。

[关键词]七叶皂苷钠;药理作用;神经保护;抗肿瘤;临床药物联用

[中图分类号] R285.6[文献标识码] A [文章编号]2095-0616（2022）10-0051-05

Pharmacological effects and clinical drug combination of sodium aescinate

XUFei1GUODongkai1JIShiliang1JIANGYiguo1WANGCheng2

1. Department of Pharmacy， the Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University， Jiangsu， Suzhou 215153， China;2. Nanjing Medical University， Jiangsu， Nanjing 211100， China

[Abstract] As a natural plant medicine， sodium aescinate has many pharmacological effects， such as anti- inflammatory，anti-edema， anti-exudation， anti-free radical， anti-secretion， regulating blood lipid， lowering blood glucose， protecting nerve and anti-tumor. In addition， sodium aescinate has good efficacy in clinical application when used in combination with other drugs. In this paper， the pharmacological effects and drug interactions of sodium aescinate at home and abroad are reviewed.

[Key words] Sodium aescinate; Pharmacological action; Neuroprotection; Antitumor; Combination of clinical drugs

七叶皂苷钠（sodium aescinate， SA）是从七叶树科植物天师栗的干燥成熟种子中提取得到的主要活性成分[1]。（剩余9356字）

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