离心式血泵多相流模拟与叶轮优化

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中图分类号：R318.1 文献标志码：A

Multiphase flow simulation and impeller optimization of centrifugal blood pump

ZENG Bolin， DONG Wuhan， DANG Mengyuan， YANG Chun， GAO Ming， ZHANG Lixin （SchoolofEnergyandPowerEngineering， UniversityofShanghaiforScienceandTechnologyShanghai 2Oo93，China）

Abstract： The geometry of the impeller of a centrifugal blood pump has a significant effect on the hydraulic and hemolytic characteristics of the blood pump. In this study， a numerical simulation of the HeartWare ventricular assist device （HVAD） was performed based on the multiphase flow method to investigate the effects of flow channel width and top clearance on the hydraulic performance （head and efficiency） and hemolytic performance （normalized index of hemolysis） of the blood pump by analyzing the flow field and shear distribution of the blood pump. The results of the study show that the head of the blood pump increases with the increase of the impeler runner width， but the increase of the width leads to the expansion of the recirculation and stagnation area at the outlet of the impeler runner， which accelerates the formation of thrombus. The top clearance has less influence on the hydraulic performance of the blood pump， but increasing the top clearance helps to improve the hemolytic performance， and as the top clearance increases， the proportion of high shear force is significantly reduced， and the standard hemolytic index of the blood pump is also significantly reduced. In the comprehensive analysis， when the width of the impeller channel is 3.8mm and the top clearance is 70μm ， the head and efficiency of the blood pump are 76.622 8mmHg and 29.2535% respectively， and the standard hemolytic index of the blood pump is 0.00497g/100L . At this time， the blood pump has good blood compatibility as well as providing certain hydraulic performance. The results of this study can provide some reference for the structural improvement of HVAD.

Keywords： centrifugal blood pump; multiphase flow model; flow field analysis; hemolysis; optimization design

心血管疾病是全球最常见的死亡原因之一。（剩余13724字）