基于数据挖掘探讨《妇科冰鉴》“月经门”用药组方规律

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关键词：《妇科冰鉴》；柴得华；月经病；用药组方规律；数据挖掘技术

中图分类号：R271文獻标志码：A文章编号：1007-2349（2024）03-0042-06

Exploration of the Medication Composition Rule of Menstruation

in Gynecological Judgement Based on Data Mining

LIU Hui，AO Qiang，TAN Meng-chen，LIU Wen-e

（The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine，Changsha 410007，China）

【Abstract】Objective： To explore the the medication composition rule of menstruation in Gynecological Judgement based on data mining，Methods： The prescriptions for menstruation contained in Gynecological Judgement were collected and the herb compositions were sorted out and standardized. The data was entered and the database was established by Mircrosoft Excel 2015. By using the functions of TCM inheritance assistance platform such as frequency statistical analysis，association rule analysis and cluster analysis，the high frequency herbs and their compatibility in the compound of menstruation in Gynecological Judgement were analyzed statistically. Results： A total of 52 compounds were screened out，involving 67 herbs，with a cumulative frequency of 352 times and 11 high frequency herbs（≥10 times）. The top five herbs were angelica，ligusticum，paeoniae，cooked rehmannia，and licorice. The properties of the herbs were warm，cold and moderate and the taste were sweet，pungent and bitter. The splenic channel was the first，followed by the liver channel and then followed by the heart channel. 16 commonly used herb combinations were obtained by association analysis，and the top three were ligusticum-angelica，angelica-paeoniae and igusticum-paeoniae. 46 association rules were obtained，and the first five（confidence ≥1） were ligusticum -> angelica. cooked rehmannia，ligusticum -> angelica，cooked rehmannia，paeoniae -> angelica，ligusticum，paeoniae -> angelica，cooked rehmannia，ligusticum，paeoniae -> angelica. Finally，10 herb core combinations and 5 new prescription combinations were obtained by cluster analysis. Conclusion： For the menstruation treatment in Gynecological Judgement，the treatment of menstruation disease is the general principle of regulating qi and blood，nourishing spleen and kidney，balancing yin and yang. In the taste of modified herbs in symptomatic treatment，most of them show the odd policy.

【Key words】Gynecological Judgement; Chai Dehua; Menstrual Disease; Medication Composition Rule; Data Mining Technology

《妇科冰鉴》此书为清代柴得华通过将理论与临床相结合，在论述妇科疾病的病因病机、理法方药等方面具有独到见解的所著的一部中医药实用价值参考书，该书成书于乾隆四十一年。（剩余4744字）